The paper examines the effects of Work-life Balance and Task Performance among Female Health Workers in Sokoto State, Nigeria. Using a simple random sample, 155 female workers were selected from Four Hospitals in Sokoto State. A Questionnaire was used to obtain data, and PLSSEM v.3.0 was employed to analyze the data. Hypotheses were framed and tested statistically; the findings show a positive relationship between work-life balance and Task Performance. Similarly, This result has implications for administrators and policymakers to ensure that a favorable work condition is provided as well as provide their workers, particularly females, with the opportunity to be able to balance emotional, temporal and work demands and family responsibilities concurrently as this not only lead to worker’s commitment it also minimizes work-related sickness and accidents as well as enhance their performance. This finding has also contributed to expanding Herzberg’s two-factor theory, which primarily emphasizes the elements or factors that satisfy or dissatisfy workers.